Role of Mesenchymal Stem Cell Therapy on Healing of Corneal Wound Induced by Alkali Burn in Rats

Main Article Content

Naser A. ElSawy

Abstract

Background: Chemical injury is the common cause of corneal damage. Alkali exposure cause defective clarity and impaired vision with lack of satisfactory therapy. Bone marrow mesenchymal stem cells (BM-MSCs) are multipotent self-renewal cells and they give a hope for better treatment of many diseases.

Aim of the Review: This review aimed to show the role of subconjunctival administered BM-MSCs therapy on alkali-induced corneal burn in rats, and its effect on the damaged corneal epithelium and the area of corneal neovascularization (CNV).

Conclusion: Subconjunctival injection of MSC transplantation could accelerate corneal wound healing attenuates inflammation and reduces CNV in alkaline-burned corneas.

Keywords:
Mesenchymal stem cell, corneal injury healing, rats

Article Details

How to Cite
ElSawy, N. A. (2020). Role of Mesenchymal Stem Cell Therapy on Healing of Corneal Wound Induced by Alkali Burn in Rats. Asian Journal of Research and Reports in Ophthalmology, 2(1), 1-4. Retrieved from https://www.journalajrrop.com/index.php/AJRROP/article/view/30095
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