Asian Journal of Research and Reports in Ophthalmology https://www.journalajrrop.com/index.php/AJRROP <p style="text-align: justify;"><strong>Asian Journal of Research and Reports in Ophthalmology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJRROP/general-guideline-for-authors">Click here for Types of paper</a>) in all aspects of&nbsp;‘Ophthalmology’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;">&nbsp;</p> Asian Journal of Research and Reports in Ophthalmology en-US Asian Journal of Research and Reports in Ophthalmology Micropulse Cyclophotocoagulation Outcomes in Primary Open Angle Glaucoma https://www.journalajrrop.com/index.php/AJRROP/article/view/30124 <p><strong>Background:</strong> Micropulse cyclophotocoagulation (MPCPC) uses a pulsed application of laser energy to produce a more mild and predictable lowering of intraocular pressure (IOP) compared to traditional CPC with fewer adverse events. It is unclear if particular types of glaucoma are better suited for treatment with MPCPC. Primary open angle glaucoma (POAG) is a leading cause of visual disability in the world and is the most common form of glaucoma in the United States.&nbsp; A retrospective, observational clinical study was done in order to determine the efficacy and safety of MPCPC specifically for patients with POAG in an urban patient population at a tertiary referral academic medical center.</p> <p><strong>Methods:</strong> Patients with primary open angle glaucoma who underwent an MPCPC procedure and had never undergone previous cyclodestructive procedures were considered.&nbsp; Patients were followed for 6 consecutive months.&nbsp; IOP, number of topical glaucoma medications, and best corrected visual acuity (BCVA) were recorded prior to the laser procedure, and at follow-up intervals of 1, 3, and 6 months after the procedure. Procedural success was defined as a 20% reduction in IOP, with IOP between 6-21, and no need for subsequent glaucoma filtering surgery. A Wilxocon signed rank test was used to determine statistical significance.</p> <p><strong>Results:</strong> A total of 39 eyes in patients aged 28-82 with POAG that underwent MPCPC were included in the study. Mean baseline IOP was 22.9 mmHg, mean baseline number of drops was 3.1, and mean baseline BCVA in LogMAR notation was 1.0.&nbsp; The MPCPC procedure produced a statistically significant decrease in IOP of 42.1% (p&lt;0.001), 31.0% (p&lt;0.001), and 34.0% (p&lt;0.001) at 1, 3, and 6 months respectively. The number of required topical glaucoma drops was not significantly reduced at any of the three follow-up time points, but there was a modest trend towards requiring fewer drops. Patients met the criteria for procedural success at a rate of 74.4%.&nbsp;&nbsp;</p> <p><strong>Conclusions:</strong> Our results are consistent with the hypothesis that the MPCPC is safe and effective in lowering IOP in patients with POAG.&nbsp; Further research is needed to determine if MPCPC is equally safe and effective in other forms of glaucoma.</p> D. Dansdill K. Pikey R. Krishna ##submission.copyrightStatement## 2021-01-11 2021-01-11 1 9 The Challenge of Predicting OAG Progression from the Initial Visual Field Test https://www.journalajrrop.com/index.php/AJRROP/article/view/30125 <p><strong>Purpose:</strong> The aim of this study was the development of a critical code in order to combine statistics with a workable diagnostic system for open angle glaucoma that could predict improvement or deterioration of the tested visual field of a glaucoma suspect, most likely after the first or second visit for the visual field test.</p> <p><strong>Methods:</strong> The study plan was to apply a set of different filters in order to select the most efficient one that could remove the most of the noise of the test printout, of which probably the greater part of this removed noise could be the component of the learning effect, as it was expected to be at the first or second session. The common mean and median filters were initially used and later on an adapted or Hybrid filter was designed in MatLab© environment and in a similar philosophy to Gardiner’s Predictor filter. Taking into account the details of the study data, an Adaptive or Hybrid filter following the deployment of the optic nerve fibre layers of the retina was tested and selecting different weight depending on the locations of possible glaucoma defects.</p> <p><strong>Results: </strong>&nbsp;Initially, the used mean and median filters, used to remove noise of visual field provided ambitious results. The first filter blurred the edges and the overall appearance looked fuzzy or blurry. The second one calculated the values of the neighbourhood and set these in ascending array. Then selected the median of these values to replace the original one. The result in general looks misleading.&nbsp; Next, applying the Hybrid Adapted filter, the end results illustrated elimination of measured noise in the visual field tests and likely the first visit outcome could predict the third or the fifth visit one.</p> <p><strong>Conclusion: </strong>This is a promising approach to identify and eliminate measurement noise in the visual field tests and to predict, after filtering the first examination outcome, the likely visual field outcome of the third or the fifth visit. The challenge of predicting the progression of open angle glaucoma from the initial visit nowadays is even more than any other the “Holy Grail” of Perimetry.</p> Aristeidis Chandrinos ##submission.copyrightStatement## 2021-01-16 2021-01-16 10 28